Peptides are short chains of amino acids that act as signaling molecules in the body. Certain peptides have been shown to have appetite-suppressing effects. The main mechanisms behind their appetite suppression include:
- Increasing feelings of fullness by slowing gastric emptying and intestinal transit
- Activating areas of the brain involved in appetite regulation
- Balancing or optimizing key appetite hormones like ghrelin, leptin, and PYY
Some of the most studied
appetite-suppressing peptides include:
PYY3-36:
- A
peptide released after meals that activates Y2 receptors in the hypothalamus, decreasing appetite
- Shown to suppress appetite and food intake for up to 12 hours when administered
Glucagon-like peptide 1 (GLP-1):
- Secreted from intestinal L-cells after meals, signals satiety
- Activates GLP-1 receptors in appetite regulation pathways
- Approved as medication for weight loss
Oxyntomodulin:
- Released from the intestines after meals
- Reduces gastric emptying and gut motility, increasing feelings of fullness
L-Carnitine:
- Amino acid derivative that enhances oxidation of fat
- Shown to reduce appetite markers and increase satiety hormones
Other emerging peptides: Des-acyl ghrelin, obestatin, nesfatin-1
Some key points on appetite suppressing peptides:
- Work via gut-brain communication pathways to reduce appetite drive
- Enhance feelings of fullness, slow gastric emptying
- Optimize levels of hormones like PYY, GLP-1 that signal satiety
- Suppress neurotransmitters that stimulate appetite
- Safely promote weight loss with minimal side effects
Appetite suppressing peptides offer an emerging and promising set of tools for managing obesity. When combined with lifestyle changes, they may help optimize weight loss results.
Check out Hormone Solutions Weight Loss Peptides
We provide individually customized peptide treatment regimens to help clients:
- Suppress appetite
- Increase fat burning
- Build muscle
- Enhance energy and vitality
- Slow aging
Our highly experienced medical team analyzes your biomarkers and goals to create a tailored peptide plan just for you.
We offer peptides like:
- Ipamorelin
- Sermorelin
- Tesamorelin
- BPC-157
- TB-500
- Follistatin
- Myo-Inositol
- and more!
Contact us today for a free consultation to see if our medical peptide therapies are right for you.